Title : Expression of drug pathway proteins is independent of tumour type.

Pub. Date : 2006 Jun

PMID : 16508919






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Many enzymes are involved in controlling the disposition of irinotecan, including the cellular target (TOP1), metabolism enzymes (CES2, UGT1A1, CYP3A4, CYP3A5), and cellular transporters of the anti-cancer agent (ABCB1, ABCC1, ABCC2, ABCC3, ABCC5, ABCG2). Irinotecan ATP binding cassette subfamily C member 2 Homo sapiens