Title : Mechanisms by which clofazimine and dapsone inhibit the myeloperoxidase system. A possible correlation with their anti-inflammatory properties.

Pub. Date : 1991 Jul 15

PMID : 1650217






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Chloride stimulated the oxidation of NADH in the MPO-H2O2 system in a concentration-dependent manner (50-fold at 150 mM NaCl). NAD myeloperoxidase Homo sapiens
2 Observations demonstrating the effect of the drugs on the MPO system, are: (1) Inhibition of Cl(-)-stimulated oxidation of NADH. NAD myeloperoxidase Homo sapiens