Title : Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL.

Pub. Date : 2006 Nov

PMID : 16498455






1 Functional Relationships(s)
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1 TAK1-DN, MKK6-DN, and SB203580, but not MKK3-DN, also suppressed RANKL stimulation of NF-kappaB transcription activity in a manner dependent on p65 phosphorylation on Ser-536. SB 203580 nuclear factor kappa B subunit 1 Homo sapiens