Title : Histamine H1 receptor-stimulated interleukin 8 and granulocyte macrophage colony-stimulating factor production by bronchial epithelial cells requires extracellular signal-regulated kinase signaling via protein kinase C.

Pub. Date : 2006

PMID : 16491014






1 Functional Relationships(s)
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1 Ro-31-8220, a PKC inhibitor, and PD98059, a mitogen-activated protein/ERK kinase inhibitor, suppressed the histamine-induced ERK activation and the production of granulocyte macrophage colony-stimulating factor and IL-8. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one colony stimulating factor 2 Homo sapiens