Title : Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.

Pub. Date : 2006 Feb 28

PMID : 16489767






1 Functional Relationships(s)
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1 However, the ability of Pgp substrates (such as prazosin) to stimulate ATP hydrolysis and facilitate vanadate-induced trapping of [alpha-(32)P]-8-azido-ADP is substantially affected in the presence of cis-(Z)-flupentixol. Prazosin ATP binding cassette subfamily B member 1 Homo sapiens