Pub. Date : 2006 Feb 15
PMID : 16489053
18 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 2 | 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 3 | 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 4 | 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 5 | 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 6 | 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 7 | 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 8 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 9 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 10 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 11 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 12 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 13 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 14 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 15 | These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 16 | In a chromatin immunoprecipitation assay, PCB and 3MC enhanced ER alpha (but not AhR) association with the estrogen-responsive region of the pS2 gene promoter. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 17 | These results show that PCB and 3MC directly activate ER alpha-dependent transactivation and extend the number of ligands that activate both AhR and ER alpha. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |
| 18 | These results show that PCB and 3MC directly activate ER alpha-dependent transactivation and extend the number of ligands that activate both AhR and ER alpha. | Methylcholanthrene | estrogen receptor 1 | Homo sapiens |