PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16489053-0 2006 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Methylcholanthrene 0-20 estrogen receptor 1 Homo sapiens 84-107 16489053-1 2006 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. Methylcholanthrene 0-20 estrogen receptor 1 Homo sapiens 148-171 16489053-1 2006 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. Methylcholanthrene 0-20 estrogen receptor 1 Homo sapiens 173-181 16489053-1 2006 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. Methylcholanthrene 22-25 estrogen receptor 1 Homo sapiens 148-171 16489053-1 2006 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. Methylcholanthrene 22-25 estrogen receptor 1 Homo sapiens 173-181 16489053-1 2006 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. Methylcholanthrene 104-107 estrogen receptor 1 Homo sapiens 148-171 16489053-1 2006 3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions. Methylcholanthrene 104-107 estrogen receptor 1 Homo sapiens 173-181 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 27-30 estrogen receptor 1 Homo sapiens 57-65 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 27-30 estrogen receptor 1 Homo sapiens 107-115 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 27-30 estrogen receptor 1 Homo sapiens 107-115 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 27-30 estrogen receptor 1 Homo sapiens 107-115 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 206-209 estrogen receptor 1 Homo sapiens 57-65 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 206-209 estrogen receptor 1 Homo sapiens 107-115 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 206-209 estrogen receptor 1 Homo sapiens 107-115 16489053-4 2006 These results suggest that 3MC and PCB directly activate ER alpha, and this was confirmed in a competitive ER alpha binding assay and in a fluorescence resonance energy transfer experiment in which PCB and 3MC induced CFP-ER alpha/YFP-ER alpha interactions. Methylcholanthrene 206-209 estrogen receptor 1 Homo sapiens 107-115 16489053-5 2006 In a chromatin immunoprecipitation assay, PCB and 3MC enhanced ER alpha (but not AhR) association with the estrogen-responsive region of the pS2 gene promoter. Methylcholanthrene 50-53 estrogen receptor 1 Homo sapiens 63-71 16489053-7 2006 These results show that PCB and 3MC directly activate ER alpha-dependent transactivation and extend the number of ligands that activate both AhR and ER alpha. Methylcholanthrene 32-35 estrogen receptor 1 Homo sapiens 54-62 16489053-7 2006 These results show that PCB and 3MC directly activate ER alpha-dependent transactivation and extend the number of ligands that activate both AhR and ER alpha. Methylcholanthrene 32-35 estrogen receptor 1 Homo sapiens 149-157