Title : Phorbol and calcium decreased atriopeptin response in a human renal cell line.

Pub. Date : 1991 Mar-Apr

PMID : 1648714






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phorbol 12-myristate 13-acetate (PMA), a protein kinase C (PKC) activator, and A23187 and its 4-bromo derivative, calcium ionophores, inhibited ANF-s-cGMP in a dose-dependent manner. Tetradecanoylphorbol Acetate natriuretic peptide A Homo sapiens
2 Phorbol 12-myristate 13-acetate (PMA), a protein kinase C (PKC) activator, and A23187 and its 4-bromo derivative, calcium ionophores, inhibited ANF-s-cGMP in a dose-dependent manner. Tetradecanoylphorbol Acetate natriuretic peptide A Homo sapiens
3 Thirty-six hour preincubation with PMA, a procedure used to down-regulate PKC, abolished acute PMA inhibition of ANF-s-cGMP without having an effect on ANF-s-cGMP or on 4-bromo-A23187 inhibition thereof. Tetradecanoylphorbol Acetate natriuretic peptide A Homo sapiens