Title : Trkb receptors modulation of glutamate release is limited to a subset of nerve terminals in the adult rat hippocampus.

Pub. Date : 2006 Apr

PMID : 16477614






2 Functional Relationships(s)
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1 BDNF, at 100 ng/ml, potentiated by 25% the K(+)-evoked release of [(3)H]glutamate from hippocampal synaptosomes. [(3)h]glutamate brain-derived neurotrophic factor Rattus norvegicus
2 The small effect of BDNF on [(3)H]glutamate release correlated with a modest increase in phospholipase Cgamma (PLCgamma) phosphorylation, and with the lack of effect of BDNF on extracellular-signal regulated kinase (ERK) and Akt phosphorylation. [(3)h]glutamate brain-derived neurotrophic factor Rattus norvegicus