Title : Induction of apoptosis in neoplastic cells by depletion of vitamin B12.

Pub. Date : 1997 Apr

PMID : 16465233






1 Functional Relationships(s)
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1 Using nitrous oxide to inactivate vitamin B12 we show that, in a variety of cell lines in vitro, methionine synthase is rapidly inhibited, the cells cease proliferation and undergo apoptosis. Nitrous Oxide NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens