Title : Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways.

Pub. Date : 2006 Mar 25

PMID : 16458870






1 Functional Relationships(s)
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1 Our investigation demonstrated that luteolin similar to PD98059, which acts as a specific inhibitor of MEK, an up stream kinase regulating ERK1/2, and wortmannin, a PI3K inhibitor, inhibited the invasiveness induced by HGF. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one hepatocyte growth factor Homo sapiens