Title : CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress.

Pub. Date : 2006 Feb 15

PMID : 16455964






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A significant number of CD11b(+)/Gr-1(+) cells expressing arginase 1 accumulated in T cell zones around the germinal centers of the white pulp of the spleen within 6 h of trauma and lasted for at least 72 h. Increased arginase activity and arginase 1 expression, along with increased [(3)H]arginine uptake, l-arginine depletion, and l-ornithine accumulation in the culture medium, were observed exclusively in CD11b(+)/Gr-1(+) cells after traumatic stress. Ornithine integrin subunit alpha M Homo sapiens