Title : Insulin activates GTP binding to a 40 kDa protein in fat cells.

Pub. Date : 1991 May 15

PMID : 1645524






3 Functional Relationships(s)
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1 Furthermore, binding of GTP to these plasma membranes inhibited both the binding of 125I-insulin to the insulin receptor and the stimulation of the insulin receptor kinase, suggesting a feedback interaction between the insulin-stimulated GTP-binding site and the insulin receptor. Guanosine Triphosphate insulin receptor Homo sapiens
2 Furthermore, binding of GTP to these plasma membranes inhibited both the binding of 125I-insulin to the insulin receptor and the stimulation of the insulin receptor kinase, suggesting a feedback interaction between the insulin-stimulated GTP-binding site and the insulin receptor. Guanosine Triphosphate insulin receptor Homo sapiens
3 In conclusion, in plasma membranes of fat cells and skeletal muscle, the insulin receptor interacts with a 40 kDa GTP-binding site. Guanosine Triphosphate insulin receptor Homo sapiens