Pub. Date : 1991 Jun 5
PMID : 1645342
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 261, 2434-2440) that ganglioside GM3 inhibited epidermal growth factor (EGF)-stimulated phosphorylation of the EGF receptor in Triton X-100-treated preparations of human epidermoid carcinoma (A431) cell membranes. | Gangliosides | epidermal growth factor | Homo sapiens |
| 2 | 261, 2434-2440) that ganglioside GM3 inhibited epidermal growth factor (EGF)-stimulated phosphorylation of the EGF receptor in Triton X-100-treated preparations of human epidermoid carcinoma (A431) cell membranes. | Gangliosides | epidermal growth factor | Homo sapiens |
| 3 | 261, 2434-2440) that ganglioside GM3 inhibited epidermal growth factor (EGF)-stimulated phosphorylation of the EGF receptor in Triton X-100-treated preparations of human epidermoid carcinoma (A431) cell membranes. | Gangliosides | epidermal growth factor | Homo sapiens |
| 4 | In contrast, a modified ganglioside, de-N-acetyl GM3, enhanced the EGF-dependent tyrosine kinase activity of the EGF receptor. | Gangliosides | epidermal growth factor | Homo sapiens |
| 5 | In contrast, a modified ganglioside, de-N-acetyl GM3, enhanced the EGF-dependent tyrosine kinase activity of the EGF receptor. | Gangliosides | epidermal growth factor | Homo sapiens |
| 6 | We also demonstrate that ganglioside GM3 inhibited EGF-stimulated growth of transfected murine fibroblasts (3T3) that express the gene for human EGF receptor (Velu, T. J., Beguinot, L., Vass, W. C., Zhang, K., Pastan, I., and Lowy, D. R. (1989) J. | Gangliosides | epidermal growth factor | Homo sapiens |
| 7 | These studies indicate that ganglioside GM3, but not its deacetylated analogue, can affect EGF receptor kinase activity in intact membranes. | Gangliosides | epidermal growth factor | Homo sapiens |