Pub. Date : 2006 Apr
PMID : 16434501
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We applied the 4D system to study the effect of 100 microM cadmium exposure on shh expression. | Cadmium | sonic hedgehog signaling molecule a | Danio rerio |
| 2 | In control zebrafish embryos, shh:GFP expression was detected at about 9 h post-fertilization (hpf) and increased steadily in the next 7 h, peaking at about 17 hpf and decreasing in the following 4 h. In the same time period, different shh expression volumes were observed in cadmium-treated and control embryos. | Cadmium | sonic hedgehog signaling molecule a | Danio rerio |
| 3 | Embryos affected by cadmium-exposure demonstrated a down-regulation in shh expression. | Cadmium | sonic hedgehog signaling molecule a | Danio rerio |
| 4 | The number of GFP-expressing cells measured by flow cytometry decreased, and expression of neurogenin-1, a downstream target of the shh signaling pathway, was down-regulated, providing additional supporting data on the effects of cadmium on shh. | Cadmium | sonic hedgehog signaling molecule a | Danio rerio |
| 5 | The number of GFP-expressing cells measured by flow cytometry decreased, and expression of neurogenin-1, a downstream target of the shh signaling pathway, was down-regulated, providing additional supporting data on the effects of cadmium on shh. | Cadmium | sonic hedgehog signaling molecule a | Danio rerio |