PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16434501-4	2006	We applied the 4D system to study the effect of 100 microM cadmium exposure on shh expression.	Cadmium	59-66	sonic hedgehog signaling molecule a	Danio rerio	79-82	
16434501-5	2006	In control zebrafish embryos, shh:GFP expression was detected at about 9 h post-fertilization (hpf) and increased steadily in the next 7 h, peaking at about 17 hpf and decreasing in the following 4 h. In the same time period, different shh expression volumes were observed in cadmium-treated and control embryos.	Cadmium	276-283	sonic hedgehog signaling molecule a	Danio rerio	30-33	
16434501-6	2006	Embryos affected by cadmium-exposure demonstrated a down-regulation in shh expression.	Cadmium	20-27	sonic hedgehog signaling molecule a	Danio rerio	71-74	
16434501-7	2006	The number of GFP-expressing cells measured by flow cytometry decreased, and expression of neurogenin-1, a downstream target of the shh signaling pathway, was down-regulated, providing additional supporting data on the effects of cadmium on shh.	Cadmium	230-237	sonic hedgehog signaling molecule a	Danio rerio	132-135	
16434501-7	2006	The number of GFP-expressing cells measured by flow cytometry decreased, and expression of neurogenin-1, a downstream target of the shh signaling pathway, was down-regulated, providing additional supporting data on the effects of cadmium on shh.	Cadmium	230-237	sonic hedgehog signaling molecule a	Danio rerio	241-244