Title : Cytogenetic biomarkers, urinary metabolites and metabolic gene polymorphisms in workers exposed to styrene.

Pub. Date : 2006 Feb

PMID : 16424821






2 Functional Relationships(s)
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1 The possible influence of genetic polymorphisms of xenobiotic-metabolizing enzymes involved in styrene biotransformation (EPHX1, GSTT1, GSTM1, GSTP1) and NAT2 on the cytogenetic endpoints was investigated. Styrene glutathione S-transferase theta 1 Homo sapiens
2 Our results suggest that occupational exposure to styrene has genotoxic effects that are potentiated by the GSTT1 gene deletion. Styrene glutathione S-transferase theta 1 Homo sapiens