Pub. Date : 2006 Jan 15
PMID : 16424033
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gefitinib suppressed gemcitabine-mediated p(Y845)EGFR stimulation. | gemcitabine | epidermal growth factor receptor | Homo sapiens |
| 2 | The schedule of gefitinib followed by gemcitabine also caused suppression of p(Y845)EGFR but arrested cells in G(1). | gemcitabine | epidermal growth factor receptor | Homo sapiens |
| 3 | These findings suggest that the schedule of gemcitabine followed by gefitinib may increase the therapeutic index over gemcitabine alone and, combined with clinical data, encourage exploration of combination of gemcitabine, EGFR inhibitors, and radiation. | gemcitabine | epidermal growth factor receptor | Homo sapiens |