Title : Effect of propofol on ropivacaine metabolism in human liver microsomes.

Pub. Date : 2006

PMID : 16421682






1 Functional Relationships(s)
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1 Propofol shows a competitive inhibitory effect on the metabolism of ropivacaine (i.e., PPX production mediated by CYP3A4) in human CYP systems in vitro. Propofol cytochrome P450 family 3 subfamily A member 4 Homo sapiens