Title : Styrene monomer primarily induces CYP2B1 mRNA in rat liver.

Pub. Date : 2005 Dec

PMID : 16418063






2 Functional Relationships(s)
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1 Significant increases in the amount of CYP2E1, CYP1A2 and CYP2B2 mRNA were also observed after styrene exposure, and their increase levels were 3.1-, 1.7- and 1.7-fold higher than controls, respectively. Styrene cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus
2 Western blot analysis also indicated that the protein levels of CYP2B1, CYP2B2, CYP2E1 and CYP1A2 showed clear increases after styrene treatment, corresponding to their mRNA expression. Styrene cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus