Title : Protein kinase C enhances glycine-insensitive desensitization of NMDA receptors independently of previously identified protein kinase C sites.

Pub. Date : 2006 Mar

PMID : 16417568






2 Functional Relationships(s)
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1 In HEK293 cells expressing NR1/NR2A, activation of endogenous PKC by 4beta-phorbol 12-myristate 13-acetate (PMA) increased NMDAR desensitization as evidenced by a reduced steady-state current without any change in peak. Tetradecanoylphorbol Acetate glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens
2 In HEK293 cells expressing NR1/NR2A, activation of endogenous PKC by 4beta-phorbol 12-myristate 13-acetate (PMA) increased NMDAR desensitization as evidenced by a reduced steady-state current without any change in peak. Tetradecanoylphorbol Acetate glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens