Title : Regulation by sphingosine 1-phosphate of Bax and Bad activities during apoptosis in a MEK-dependent manner.

Pub. Date : 2006 Feb 24

PMID : 16414356






2 Functional Relationships(s)
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Protein Name
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1 First, sphingosine 1-phosphate treatment results in Bad inactivation via the ERK/Rsk-1 pathway. sphingosine 1-phosphate mitogen-activated protein kinase 1 Homo sapiens
2 Hence, the MEK/ERK pathway seems to be crucial for the survival effects initiated by sphingosine 1-phosphate. sphingosine 1-phosphate mitogen-activated protein kinase 1 Homo sapiens