Title : Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1).

Pub. Date : 2006 Jan

PMID : 16411661






1 Functional Relationships(s)
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1 A practical application of the receptor-based screen developed here with RyR1 is that it provides a quantitative SAR that may be useful in predicting biological activity and risk of mixtures containing noncoplanar PCB congeners that have low or a lack of aryl hydrocarbon receptor activity. Polychlorinated Biphenyls aryl hydrocarbon receptor Homo sapiens