Title : Vascular endothelial growth factor signalling in endothelial cell survival: a role for NFkappaB.

Pub. Date : 2006 Feb 17

PMID : 16410078






2 Functional Relationships(s)
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1 Instead, tyrosine phosphorylation of IkappaBalpha was observed following VEGF treatment, suggesting NFkappaB activation was mediated by degradation-independent dissociation of IkappaBalpha from NFkappaB. Tyrosine NFKB inhibitor alpha Homo sapiens
2 Adenovirus-mediated over-expression of either native IkappaBalpha, or of IkappaBalpha in which tyrosine residue 42 was mutated to phenylalanine, inhibited induction of NFkappaB-dependent luciferase activity in response to VEGF. Tyrosine NFKB inhibitor alpha Homo sapiens