Title : Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers.

Pub. Date : 2006 Jan 17

PMID : 16407140






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we found that, by using fluorescent tags and immunoprecipitation assays, NEPPs are taken up preferentially into neurons and bind in a thiol-dependent manner to Keap1, a negative regulator of the transcription factor Nrf2. Sulfhydryl Compounds NFE2 like bZIP transcription factor 2 Homo sapiens