Title : Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells.

Pub. Date : 2005 Dec 31

PMID : 16391520






1 Functional Relationships(s)
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1 These results clearly show that PGE2 increased angiogenesis by activating the NO/cGMP signaling pathway through PKA/PI3K/Akt-dependent increase in eNOS activity. Cyclic GMP AKT serine/threonine kinase 1 Homo sapiens