Title : Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane.

Pub. Date : 2005 Dec

PMID : 16359182






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sulforaphane exerts cancer chemopreventive effects by inducing antioxidant/electrophile response element (ARE)-regulated phase 2 enzyme and antioxidant genes through activation of the transcription factor nuclear factor-E2-related factor 2 (Nrf2), which is regulated by the thiol-rich sensor protein Kelch-like ECH-associated protein 1 (Keap1). Sulfhydryl Compounds NFE2 like bZIP transcription factor 2 Homo sapiens
2 Sulforaphane exerts cancer chemopreventive effects by inducing antioxidant/electrophile response element (ARE)-regulated phase 2 enzyme and antioxidant genes through activation of the transcription factor nuclear factor-E2-related factor 2 (Nrf2), which is regulated by the thiol-rich sensor protein Kelch-like ECH-associated protein 1 (Keap1). Sulfhydryl Compounds NFE2 like bZIP transcription factor 2 Homo sapiens