Title : Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients.

Pub. Date : 2006 Jan

PMID : 16341266






2 Functional Relationships(s)
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1 We previously reported that human CD4+ Tregs secrete high levels of IL-10 when stimulated in the presence of dexamethasone and calcitriol (vitamin D3). Cholecalciferol CD4 molecule Homo sapiens
2 Addition of vitamin D3 with dexamethasone to cultures of SR CD4+ T cells enhanced IL-10 synthesis to levels observed in cells from glucocorticoid-sensitive patients cultured with dexamethasone alone. Cholecalciferol CD4 molecule Homo sapiens