Title : Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia.

Pub. Date : 2005

PMID : 16339656






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Remarkably, binding of AHSP to oxygenated alphaHb induces dramatic conformational changes and converts the heme-bound iron to an oxidized hemichrome state in which all six coordinate positions are occupied. Iron alpha hemoglobin stabilizing protein Mus musculus
2 This structure limits the reactivity of heme iron, providing a mechanism by which AHSP stabilizes alphaHb. Iron alpha hemoglobin stabilizing protein Mus musculus