PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16338954-10	2006	Arsenite raised the levels of phospho-p53 (serine-15) and p53 (DO-1) proteins in both the securin-wild-type and -null cells.	arsenite	0-8	tumor protein p53	Homo sapiens	38-41	
16338954-10	2006	Arsenite raised the levels of phospho-p53 (serine-15) and p53 (DO-1) proteins in both the securin-wild-type and -null cells.	arsenite	0-8	tumor protein p53	Homo sapiens	58-61	
16338954-11	2006	The p53-functional cells were more susceptible than the p53-mutational cells to arsenite on the cytotoxicity and apoptosis.	arsenite	80-88	tumor protein p53	Homo sapiens	4-7	
16338954-11	2006	The p53-functional cells were more susceptible than the p53-mutational cells to arsenite on the cytotoxicity and apoptosis.	arsenite	80-88	tumor protein p53	Homo sapiens	56-59	
16338954-12	2006	Besides, arsenite decreased the levels of securin proteins to a similar degree in both the p53-functional and -mutational cells.	arsenite	9-17	tumor protein p53	Homo sapiens	91-94	
16338954-13	2006	Together, it is the first time to demonstrate that the inhibition of securin expression induced by arsenite increases the chromosomal instability and apoptosis via a p53-independent pathway.	arsenite	99-107	tumor protein p53	Homo sapiens	166-169