Title : ERK-dependent signaling pathway and transcriptional factor Ets-1 regulate matrix metalloproteinase-9 production in transforming growth factor-beta1 stimulated glomerular podocytes.

Pub. Date : 2005

PMID : 16301820






1 Functional Relationships(s)
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1 However, blockade of Smad2 signaling pathway by Staurosporine did not affect the TGFbeta1-stimulated secretion of MMP-9, whereas inhibition of activation of ERK1/2 by PD98059 abolished TGFbeta1-stimulated secretion of MMP-9 and expression of MMP-9 mRNA. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one transforming growth factor, beta 1 Mus musculus