Title : Effects of aryl hydrocarbon receptor signaling on the modulation of TH1/TH2 balance.

Pub. Date : 2005 Dec 1

PMID : 16301641






4 Functional Relationships(s)
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1 In this report, we determined that M50354 (an active metabolite of M50367) was a ligand for the aryl hydrocarbon receptor (AhR); the immunological effects of this compound on in vitro Th1/Th2 differentiation from naive Th cells and Th1/Th2 balance in vivo were manifested through binding to AhR. M50354 aryl-hydrocarbon receptor Mus musculus
2 In this report, we determined that M50354 (an active metabolite of M50367) was a ligand for the aryl hydrocarbon receptor (AhR); the immunological effects of this compound on in vitro Th1/Th2 differentiation from naive Th cells and Th1/Th2 balance in vivo were manifested through binding to AhR. M50354 aryl-hydrocarbon receptor Mus musculus
3 In this report, we determined that M50354 (an active metabolite of M50367) was a ligand for the aryl hydrocarbon receptor (AhR); the immunological effects of this compound on in vitro Th1/Th2 differentiation from naive Th cells and Th1/Th2 balance in vivo were manifested through binding to AhR. M50354 aryl-hydrocarbon receptor Mus musculus
4 Suppression of naive Th cell differentiation into Th2 cells via binding of M50354 to AhR was associated with inhibition of GATA-3 expression in Th cells. M50354 aryl-hydrocarbon receptor Mus musculus