Title : Phosphorylation of P-Rex1 by the cyclic AMP-dependent protein kinase inhibits the phosphatidylinositiol (3,4,5)-trisphosphate and Gbetagamma-mediated regulation of its activity.

Pub. Date : 2006 Jan 27

PMID : 16301320






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phosphorylation of P-Rex1 with protein kinase A (PKA) inhibits the PIP(3)- and Gbetagamma-stimulated P-Rex1 guanine nucleotide exchange activity on Rac. pip(3) phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Homo sapiens
2 Phosphorylation of P-Rex1 with protein kinase A (PKA) inhibits the PIP(3)- and Gbetagamma-stimulated P-Rex1 guanine nucleotide exchange activity on Rac. pip(3) phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Homo sapiens