Pub. Date : 2005 Dec
PMID : 16291719
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Alfentanil-induced miosis clearance as a liver CYP3A4 and 3A5 activity measure in healthy volunteers: improvement of experimental conditions. | Alfentanil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | The aims of this study were to demonstrate the correlation between alfentanil-induced miosis evaluation and alfentanil pharmacokinetics (PK) as a CYP3A4 and 3A5 activity probe in volunteers and to explain the variability in pupilar response and in alfentanil PK. | Alfentanil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | The aims of this study were to demonstrate the correlation between alfentanil-induced miosis evaluation and alfentanil pharmacokinetics (PK) as a CYP3A4 and 3A5 activity probe in volunteers and to explain the variability in pupilar response and in alfentanil PK. | Alfentanil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 4 | The aims of this study were to demonstrate the correlation between alfentanil-induced miosis evaluation and alfentanil pharmacokinetics (PK) as a CYP3A4 and 3A5 activity probe in volunteers and to explain the variability in pupilar response and in alfentanil PK. | Alfentanil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 5 | Alfentanil-induced miosis clearance as a noninvasive CYP3A4 and 3A5 activity measure can be done in both ambient and dark conditions. | Alfentanil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |