Title : RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.

Pub. Date : 2005 Dec

PMID : 16287852






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We identify the CtIP and CtBP corepressors as novel components of the human RBP-Jkappa/SHARP-corepressor complex and show that CtIP binds directly to the SHARP repression domain. ctbp recombination signal binding protein for immunoglobulin kappa J region Homo sapiens
2 We propose that a corepressor complex containing CtIP/CtBP facilitates RBP-Jkappa/SHARP-mediated repression of Notch target genes. ctbp recombination signal binding protein for immunoglobulin kappa J region Homo sapiens