Title : Opposing effects of oestradiol and progesterone on intracellular pathways and activation processes in the oxidative stress induced activation of cultured rat hepatic stellate cells.

Pub. Date : 2005 Dec

PMID : 16284289






1 Functional Relationships(s)
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1 Progesterone exerted a stimulatory effect through the progesterone receptor on the induction of ROS generation processes and intracellular pathways, resulting in TGF-beta1 expression and HSC activation, and fibrogenic effects were inhibited by oestradiol. Progesterone progesterone receptor Rattus norvegicus