Pub. Date : 2006 Mar
PMID : 16282336
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Eicosapentaenoic acid ameliorates diabetic nephropathy of type 2 diabetic KKAy/Ta mice: involvement of MCP-1 suppression and decreased ERK1/2 and p38 phosphorylation. | Eicosapentaenoic Acid | chemokine (C-C motif) ligand 2 | Mus musculus |
| 2 | RESULTS: EPA decreased the levels of serum triglycerides, leptin, urinary albumin and MCP-1, and improved glucose intolerance, mesangial matrix accumulation and tubulointerstitial fibrosis in KKAy/Ta mice. | Eicosapentaenoic Acid | chemokine (C-C motif) ligand 2 | Mus musculus |
| 3 | Immunohistochemical staining of MCP-1 and F4/80 in the glomeruli and tubulointerstitial regions was decreased in the EPA-treated group. | Eicosapentaenoic Acid | chemokine (C-C motif) ligand 2 | Mus musculus |
| 4 | EPA and specific inhibitors of ERK1/2, JNK and PI3K decreased levels of MCP-1 in MMCs. | Eicosapentaenoic Acid | chemokine (C-C motif) ligand 2 | Mus musculus |