Title : SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity.

Pub. Date : 2005 Dec 7

PMID : 16281056






2 Functional Relationships(s)
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1 We have created P1 artificial chromosome transgenic mice expressing the human mitochondrial superoxide dismutase 2 (SOD2) and thus generated mice with a physiologically controlled augmentation of SOD2 expression leading to increased SOD2 enzyme activities and lowered superoxide levels. Superoxides superoxide dismutase 2, mitochondrial Mus musculus
2 We have created P1 artificial chromosome transgenic mice expressing the human mitochondrial superoxide dismutase 2 (SOD2) and thus generated mice with a physiologically controlled augmentation of SOD2 expression leading to increased SOD2 enzyme activities and lowered superoxide levels. Superoxides superoxide dismutase 2, mitochondrial Mus musculus