Title : Triazine-based tyrosinase inhibitors identified by chemical genetic screening.

Pub. Date : 2005 Dec

PMID : 16280010






1 Functional Relationships(s)
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1 Kinetic data suggest that all four compounds act as competitive inhibitors of tyrosinase, most likely competing with L-3,4-dihydroxyphenylalanine (L-DOPA) for binding to the DOPA-binding site of the enzyme. Dihydroxyphenylalanine tyrosinase Homo sapiens