Title : Pharmacogenetics of irinotecan metabolism and transport: an update.

Pub. Date : 2006 Mar

PMID : 16271446






2 Functional Relationships(s)
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1 Elimination of irinotecan is also dependent on drug-transporting proteins, notably ABCB1 (P-glycoprotein), ABCC2 (cMOAT) and ABCG2 (BCRP), present on the bile canalicular membrane. Irinotecan ATP binding cassette subfamily C member 2 Homo sapiens
2 Elimination of irinotecan is also dependent on drug-transporting proteins, notably ABCB1 (P-glycoprotein), ABCC2 (cMOAT) and ABCG2 (BCRP), present on the bile canalicular membrane. Irinotecan ATP binding cassette subfamily C member 2 Homo sapiens