Title : Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA.

Pub. Date : 2006 Feb 9

PMID : 16247472






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, ECT2 T412A, but not phosphomimic T412D, displayed a diminished accumulation of GTP-bound RhoA compared with WT ECT2, suggesting that phosphorylation of Thr-412 is critical for the catalytic activity of ECT2. Threonine ras homolog family member A Homo sapiens