Title : Higher frequency of HIV-1-specific T cell immune responses in African American children vertically infected with HIV-1.

Pub. Date : 2005 Nov 15

PMID : 16235176






1 Functional Relationships(s)
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1 After adjustment for CD4(+) count, age, and log(10) viral load, African American children demonstrated significantly higher Gag responses (average, 486 spot-forming cells higher; P=.01) than Hispanic children; this was significantly driven by robust responses in African American girls near the age of puberty, many of whom carried the human leukocyte antigen class I B*58 allele. Glycosaminoglycans major histocompatibility complex, class I, B Homo sapiens