Pub. Date : 2005 Oct
PMID : 16227395
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells. | Resveratrol | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 2 | Our results showed that resveratrol significantly inhibited both basal level and hypoxia-induced HIF-1alpha protein accumulation in cancer cells, but did not affect HIF-1alpha mRNA levels. | Resveratrol | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 3 | These data suggested that HIF-1alpha/VEGF could be a promising drug target for resveratrol in the development of an effective chemopreventive and anticancer therapy in human cancers. | Resveratrol | hypoxia inducible factor 1 subunit alpha | Homo sapiens |