Title : Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.

Pub. Date : 2005 Oct 15

PMID : 16214399






6 Functional Relationships(s)
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1 The apparent K(m) values of recombinant DGAT1/ARAT for retinol and palmitoyl coenzyme A were determined to be 25.9+/-2.1 microM and 13.9+/-0.3 microM, respectively, both of which are similar to the values previously determined for ARAT in native tissues. Vitamin A diacylglycerol O-acyltransferase 1 Homo sapiens
2 The apparent K(m) values of recombinant DGAT1/ARAT for retinol and palmitoyl coenzyme A were determined to be 25.9+/-2.1 microM and 13.9+/-0.3 microM, respectively, both of which are similar to the values previously determined for ARAT in native tissues. Vitamin A diacylglycerol O-acyltransferase 1 Homo sapiens
3 The apparent K(m) values of recombinant DGAT1/ARAT for retinol and palmitoyl coenzyme A were determined to be 25.9+/-2.1 microM and 13.9+/-0.3 microM, respectively, both of which are similar to the values previously determined for ARAT in native tissues. Vitamin A diacylglycerol O-acyltransferase 1 Homo sapiens
4 A novel selective DGAT1 inhibitor, XP620, inhibits recombinant DGAT1/ARAT at the retinol recognition site. Vitamin A diacylglycerol O-acyltransferase 1 Homo sapiens
5 A novel selective DGAT1 inhibitor, XP620, inhibits recombinant DGAT1/ARAT at the retinol recognition site. Vitamin A diacylglycerol O-acyltransferase 1 Homo sapiens
6 A novel selective DGAT1 inhibitor, XP620, inhibits recombinant DGAT1/ARAT at the retinol recognition site. Vitamin A diacylglycerol O-acyltransferase 1 Homo sapiens