Title : Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry.

Pub. Date : 2006 Feb 1

PMID : 16214344






2 Functional Relationships(s)
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1 Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Oximes O-GlcNAcase Homo sapiens
2 The potent O-GlcNAcase inhibitor PUGNAc was synthesized and two isomers based on the E and Z stereochemistry of the oxime moiety were separated, defined, and tested for activity. Oximes O-GlcNAcase Homo sapiens