Protein Name | O-GlcNAcase |
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Organism | Homo sapiens |
Gene ID | 10724 |
Gene Symbol | OGA |
UniProt | O60502 (OGA_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
767
Total Number of Articles : 1124 |
Description |
O-GlcNAcase |
Gene Summary |
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008] |
synonyms |
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Properties | |