Protein Name O-GlcNAcase
Organism Homo sapiens
Gene ID 10724
Gene Symbol

OGA

UniProt O60502 (OGA_HUMAN)
Relationships Total Number of functionally related compound(s) : 767
Total Number of Articles : 1124
Description

O-GlcNAcase

Gene Summary

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]

synonyms
  • protein O-GlcNAcase
  • N-acetyl-beta-D-glucosaminidase
  • N-acetyl-beta-glucosaminidase
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Properties