Title : Overexpression of COX-2, Prostaglandin E synthase-1 and prostaglandin E receptors in blood mononuclear cells and plaque of patients with carotid atherosclerosis: regulation by nuclear factor-kappaB.

Pub. Date : 2006 Jul

PMID : 16212965






1 Functional Relationships(s)
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1 In cytokine-treated cultured THP-1, the NF-kappaB inhibitors parthenolide, Bay 11-7082 and PDTC reduced COX-2, mPGES-1 and EP-1/EP-3/EP-4 expression as well as PGE2 levels. 3-(4-methylphenylsulfonyl)-2-propenenitrile GLI family zinc finger 2 Homo sapiens