Pub. Date : 2005 Aug
PMID : 16193242
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Since Angiotensin II type 1 (AT1) receptor can be involved in TNF-alpha production, we have investigated whether early short-term treatment with irbesartan, an AT1 receptor blocker, is able to limit TNF-alpha production within the heart and to improve cardiac function and geometry following MI in rats. | Irbesartan | tumor necrosis factor | Rattus norvegicus |
2 | On day 7, cardiac TNF-alpha was significantly reduced in MI rats receiving irbesartan (p < 0.05). | Irbesartan | tumor necrosis factor | Rattus norvegicus |