Title : Effect of oral glucose administration on serum potassium concentration in hemodialysis patients.

Pub. Date : 2005 Oct

PMID : 16183425






5 Functional Relationships(s)
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1 Exogenous insulin stimulates this disposal by enhancing potassium uptake into cells in hemodialysis (HD) patients and healthy subjects. Potassium insulin Homo sapiens
2 In HD patients, the decrease in serum potassium levels was dependent on the increase in serum insulin levels and was more prominent when 150 g of glucose was administered. Potassium insulin Homo sapiens
3 In HD patients, the decrease in serum potassium levels correlated negatively (r = -0.45; P < 0.001) with the increase in serum insulin levels, and maximal decrease in serum potassium levels correlated negatively (r = -0.54; P < 0.001) with maximal increase in serum insulin levels. Potassium insulin Homo sapiens
4 In HD patients, the decrease in serum potassium levels correlated negatively (r = -0.45; P < 0.001) with the increase in serum insulin levels, and maximal decrease in serum potassium levels correlated negatively (r = -0.54; P < 0.001) with maximal increase in serum insulin levels. Potassium insulin Homo sapiens
5 CONCLUSION: Endogenous production of physiological concentrations of insulin in response to exogenous glucose administration decreases serum potassium levels only in HD patients, independently of plasma aldosterone and epinephrine levels. Potassium insulin Homo sapiens