Title : Crystal structures of active SRC kinase domain complexes.

Pub. Date : 2005 Oct 21

PMID : 16168436






1 Functional Relationships(s)
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1 In contrast to purvalanol B binding in CDK2, purvalanol A binds in c-Src with a conformational change in a more open ATP pocket. 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens